Adrenaline Injection 1mL Epinephrine

NDC: 51662-1290-2

Adrenalin (Epinephrine Injection, USP) 1 mg/mL (1:1000), 1 mL Vial — HealthFirst

Active ingredient	Epinephrine 1 mg/mL (1:1000)
Dosage form	Injection, solution, single-use clear glass vial
Route	Intramuscular, Subcutaneous
Size	1 mL single-use vial
Manufacturer	HF Acquisition Co LLC, DBA HealthFirst
NDC	51662-1290-2

Indications and Usage

Indicated for the emergency treatment of allergic reactions (Type I), including anaphylaxis, which may result from insect stings, foods, drugs, sera, diagnostic testing substances, other allergens, or idiopathic or exercise-induced anaphylaxis.

Dosage and Administration

Adults and children 30 kg (66 lbs) or more: 0.3 to 0.5 mg (0.3 to 0.5 mL) intramuscularly or subcutaneously into the anterolateral thigh, repeated every 5 to 10 minutes as necessary. Children under 30 kg (66 lbs): 0.01 mg/kg (0.01 mL/kg), up to a maximum of 0.3 mg (0.3 mL) per injection, repeated every 5 to 10 minutes as necessary. Do not administer repeated injections at the same site.

Warnings and Precautions

• Do not inject into the buttock, digits, hands, or feet — risk of tissue necrosis or Clostridial infection (gas gangrene)
• Rare cases of serious skin and soft tissue infections have been reported following injection; advise patients to seek medical care for signs of infection at the injection site
• May aggravate angina pectoris or produce ventricular arrhythmias, particularly in patients with underlying heart disease; administer with caution
• Patients with hyperthyroidism, Parkinson's disease, diabetes, or pheochromocytoma are at greater risk of adverse reactions
• Contains sodium metabisulfite, which may cause allergic-type reactions in susceptible individuals; however, presence of sulfite should not preclude use in a life-threatening allergic emergency

Contraindications

None.

Adverse Reactions

Common adverse reactions include anxiety, apprehensiveness, restlessness, tremor, weakness, dizziness, sweating, palpitations, pallor, nausea, vomiting, headache, and respiratory difficulties. Arrhythmias, including fatal ventricular fibrillation, rapid rises in blood pressure producing cerebral hemorrhage, and angina have occurred.

Storage and Handling

Store at 20°C to 25°C (68°F to 77°F). Protect from light and freezing. Discard 30 days after initial use once opened. Do not use if solution is colored, cloudy, or contains particulate matter.

How Supplied

Supplied as a 1 mL single-use clear glass vial, individually pouched.

Professional use only. Clinical information summarized from FDA-approved prescribing information (Structured Product Labeling); refer to the full prescribing information via DailyMed for complete details.